Innovative Product Solutions
Horphag Research continues its quest for innovative
and powerful natural products that benefit consumers.

Their flagship ingredient, Pycnogenol®, is constantly being tested by product development against new and evolving research.

Since Pycnogenol® is derived from a consistent and reliable source, you can expect Pycnogenol product formulas to be of exceptional quality. Below are examples of exclusive, finished products and product lines recently introduced to consumers around the world.

Cardiovascular Health solution  

PycnoQ10®:
PycnoQ10® is a groundbreaking combination heart formula available exclusively at GNC stores nationwide. The product is a unique blend of Pycnogenol®, Coenzyme Q10 and CarniPure® L-Carnitine -all superior ingredients recognized for their potent antioxidant properties and cardiovascular health benefits. PycnoQ10® is a one capsule per day formula designed to help support heart health and blood vessel function. Research conducted on all three ingredients strongly suggests that PycnoQ10® is an ideal antioxidant combination that works synergistically in the body to help protect and improve overall heart health and circulation, lowers bad (LDL) cholesterol, high blood pressure and fights free radicals.


   

CoQ10+:
Japanese company Sunny Health recently introduced a new heart health product called CoQ10+ with Pycnogenol®. The product combines Pycnogenol® with Coenzyme Q10. Research has shown the antioxidant ingredients have synergistic effects on the body and work to protect and enhance the whole vascular system including blood vessel integrity, blood lipid values, circulation, blood pressure and platelet function. The product is supported by a comprehensive advertising and marketing program.


   

Paleno®:
Paleno® is a new product manufactured by Sun Pharmaceutical Industries and was launched across India this July. Dr. Schonlau introduced the product to physicians in eight different cities presenting crucial facts about the product and fielding questions. Paleno contains 25mg Pycnogenol, 200IU vitamin E and 150mg vitamin C and is used as a complementary treatment for cardiovascular diseases and diabetes in addition to prescribed medicine. Physicians prescribe Paleno during patient visits and patients can thereafter purchase more Paleno at pharmacies by presenting an empty package.


 

Beauty Cosmetic Solutions  

Restgenol®:
B&C Laboratories, a division of Sony, recently launched a new Restgenol® “Active Collagenol” line of seven cosmetic products in Japan that incorporates super antioxidant Pycnogenol® into each formula. For basic skin care, there is the Lifting Face Bar, Lifting Force Cleansing, Skin Volume Water and Day Swat Serum. And, for deep skin care, Active Collagenol Cell Nutrition tablets are available. The flagship product of the Restgenol® line is the High Class Delivery tonifying beauty cream. Active ingredients include Pycnogenol, beta glucan, nano-CoQ10 among others. The line provides women with product choices for all of their skin care needs through an array of applications.

Pycnogenol® is included in many cosmetic products because of its proven research in maintaining healthy skin. Studies found that Pycnogenol® acts as a collagen stabilizer by binding to collagen in the skin and maintaining elasticity, saving it from destruction. This action helps keep the skin firm and prevents wrinkles. The antioxidant also improves microcirculation of tiny skin capillaries which help support better oxygen, nutrient and hydration supplies to the skin.

The top selling anti-aging cosmetic Restgenol® line is sold exclusively through Sony beauty shops and esthetic salons in Japan.


   

Evelle®:
Created by Pharma Nord, Evelle® is a revolutionary natural beauty formula that is comprised of a unique blend of revitalizing nutrients that nourish the skin, hair and nails from the inside, out. Taking two supplement tablets a day provide nutrients that produce smoother, firmer, younger looking skin, shiny and lustrous hair and stronger nails.

Product ingredients include antioxidant Pycnogenol® that stabilizes and protects collagen and elastin in the skin and Bio-Marine Complex with proteins and polysaccharides, to help improve the structure and quality of the dermis resulting in smoother, suppler skin. Plant extracts with lycopene and anthoocyanidins contribute natural antioxidant benefits.

Evelle® is available in the United Kingdom, Austria, Hungary, Sweden, Thailand and Japan.


   

Derma e® Eye Lighten Dark Circle Crème:
Derma e® bodycare company adds an all-natural eye crème to their Basics Collection. Available throughout the United States, Eye Lighten Dark Circle Crème with Pycnogenol® was formulated with herbal extracts and antioxidants to diminish the appearance of dark circles, reduce puffiness, and restore skin health to the delicate skin around the eyes. The eye crème’s exclusive silky, soft formula is a unique blend of botanicals including yarrow, horse chestnut, gingko biloba, witch hazel and eyebright extracts to help strengthen leaky capillaries and reduce swelling and inflammation. Two powerful antioxidants, Pycnogenol and green tea extract, protects skin structures from free radical damage and support healthy circulation. The crème also hydrates, leaving skin around the eye brighter and radiant.


   

Iklen® Pycnogenol®:
Iklen® Pycnogenol® is a revolutionary skin lightening food supplement recently introduced by Merck. Exclusively available in France, Iklen helps reduce photo-aging and the appearance of brown spots. Active ingredients in the product are Pycnogenol, Vitamin C and E, borrage oil, primrose and colza oils.

According to clinical research on Pycnogenol, the botanical extract helps reduce the appearance of brown spots for clearer, spot free skin. Additional research on Pycnogenol’s photo-aging properties demonstrates its ability to increase skin photo protection by inhibiting inflammation which occurs in response to environmental factors like ultraviolet (UV) light exposure. The essential oils in Iklen help restore skin flexibility and tonicity.

Merck recommends taking one or two caplets a day for optimal results either alone or in association with a dermatological treatment.


   

Un Destino:
The Un Destino all natural beauty line was launched by Japanese superstar Aya Sugimoto’s company, Office Aya. Aya Sugimoto is the face of the product line and celebrity spokesperson for the marketing campaign. She is famous for her movie and singing career and is a dancer, actress and model.

There are six products containing Pycnogenol® in the Un Destino beauty line and they include an oral skin health and beauty supplement called Sabinna, a drink supplement, tonifying face cream, oil-free face cleansing gel, face and body soap and moisturizing lotion. Each beauty product contains Pycnogenol for optimal antioxidant protection and other ingredients like placenta extract, tocotrienols, vitamin E and hyaluronic acid.

Pycnogenol is a versatile super antioxidant and has an abundance of skin and beauty health benefits. Studies have demonstrated that Pycnogenol® acts as a collagen stabilizer by binding to collagen in the skin and maintaining elasticity, saving it from destruction. This action helps keep the skin firm and prevents wrinkles. It also improves microcirculation of tiny skin capillaries which help support better oxygen, nutrient and hydration supplies to the skin.


   

YZ Formula SP:
YZ Formula SP is a cosmetic product launched in Japan and is designed to help prevent photo-aging of the skin, general signs of aging, and fights off inflammatory skin conditions such as sunburn. The product contains Pycnogenol, rutin, rose petal extract and fermented cereal extract among other ingredients. The manufacturer is a company called NOEVIR, which is one of the five largest cosmetic companies in Japan.


   

Silicium:
A new line of cosmetic products have recently been unveiled in Switzerland, called Silicium from Medecine Beauty. The line contains Revitalizing Face Serum, Over-moisturizing / Over-revitalizing hand cream, Revitalizing and Firming body lotion and 24-hour Revitalizing cream. Each product contains a Vitamin C enriched formula with Pycnogenol among other natural ingredients tailored to their specific functions. The organic silicium instantly fills small wrinkles in the face and the vitamin C stimulates the epidermis promoting elasticity while Pycnogenol stops harmful free radical activity. The Silicium cosmetic line is also available in France.


 

Eye Health Solutions  

Lutegenol™:
Novartis recently introduced a powerful new eye health formula in Italy. Lutegenol™ is a combination of lutein and French maritime pine bark extract Pycnogenol® that work synergistically to provide overall eye health. Both ingredients have a good deal of scientific research published on their effectiveness on eye health.

Scientists have found that lutein, a carotenoid found in dark, green leafy vegetables and certain fruits, plays a beneficial role in eye health by helping reduce the risk of age-related macular degeneration (AMD). AMD is caused when the macula of the eye deteriorates from a lifetime of steady damage due to oxidative stress in the retina. This causes the gradual loss of central vision and patient symptoms vary depending on if they suffer from dry or wet AMD.

Pycnogenol® research indicates that its properties best protect the eye by keeping blood vessels and capillaries functioning efficiently, especially in diabetics who are prone to diabetic retinopathy. Diabetic retinopathy is a leading cause of blindness in people under the age of 60 and occurs when elevated glucose levels in the blood react within the capillaries of the retina, resulting in swollen and brittle walls that eventually lead to blood leaking into the retina causing gradual vision loss.


 

Menstrual Health Solutions  

Benefique:
Cosmetics giant Shiseido created a women’s formula called Benefique to help alleviate symptoms resulting from PMS. The unique product couples Pycnogenol with soy isoflavones - phytochemicals that are naturally occurring plant chemicals in soy products. According to scientists, daily consumption of soy isoflavones can help support better PMS health. Research demonstrates supplementing with Pycnogenol decreases the incidence of cramps and other menstrual symptoms. Moreover, Pycnogenol was awarded a US patent for use in the reduction of the pain and discomfort associated with PMS further solidifying its role in menstrual health.

 


 

Functional Beverage Solutions  

One-A-Night:
Otsuka Pharmaceutical recently launched the innovative “One-A-Night” drink with Pycnogenol®. The product is one of three “One-A-Night” formulas and each targets a specific health purpose. One-A-Night with Pycnogenol® helps combat stiff shoulder problems, which are very common in Japan and Asian countries in general. The beverage helps loosen up the shoulders and Pycnogenol® is the primary active ingredient in the drink.

The product is available on the Otsuka website and in supermarkets and convenience stores in Hiroshima prefecture. An integrated television advertising and public relations campaign is in place to introduce the products and educate consumers on their unique health benefits.

 


 

Sexual Wellness Solutions  

Prelox®:
Prelox, a patented dietary supplement for men that helps support erectile quality and revitalizes sexual performance, is a proprietary blend of L-Arginine and Pycnogenol. Together the ingredients increase nitric oxide production, stimulate circulation and blood flow and protect blood vessels from the damage that can occur from normal aging. Visit www.prelox.com for more information.

 


   

FertilOx:
An interesting new male fertility and sperm motility formula has hit the U.S. market called FertilOx. Launched by Jarrow Formulas, FertilOx is a potent combination of nutrients that support sperm antioxidant status and motility. The product includes Pycnogenol, which is backed by research supporting its healthy sperm motility along with its production of endothelial Nitric Oxide (eNO). Additionally, Acetyl-L-Carnitine Arginate (ALCA) and methylselenocysteine are included in the formula and support Pycnogenol’s mechanisms of action.


 

Travel Health Solutions  

Zinopin®:
Dr. Scurr’s® Zinopin® offers travelers relief from physical discomfort resulting from long-haul flights. Pycnogenol showed effectiveness in improving circulation and helping to prevent leg and ankle swelling. Most people notice the effects of in-flight swelling if they take their shoes off during the flight and have difficulty getting back into them at the end of the flight. Leg and ankle swelling can lead to dangerous conditions such as deep vein thrombosis (DVT). In addition to Pycnogenol, Zinopin’s special formulation includes standardized ginger extract. Ginger has been used for years to combat motion sickness. Together, the natural ingredients produce an innovative formula to ensure travelers stay healthy during long trips. Visit www.zinopin.com for more information.


 

© Horphag 2006